In one embodiment of the method, a block of digital audio data is stored in a buffer, and a set of parcor values are calculated for the block of digital audio data. The invention provides a modified virus-like particle comprising a VLP which can be loaded with immunostimulatory substances, in particular with DNA oligonucleotides containing non-methylated C and G, and particular peptides derived from MelanA linked thereto. The pneumatic pistons ride in the opposed pneumatic cylinders and include hydraulic plungers extending therefrom. The heat pipe is received in the groove. In this manner, the postal authority has access to the postage indicium without having to apply it to the mail piece. The compositions, devices, and grafts typically include an effective amount of a CTP synthase 1 inhibitor to reduce proliferation of vascular smooth muscle cells, without substantial reducing the proliferation of endothelial cells.