The present invention provides a collagen accumulation inhibitor, a collagen accumulation-inhibiting method, a method for searching for a substance which regulates the type-I collagen gene transcription regulating ability and the like, said matters being useful in a medical field for a prophylaxis or the treatment of a disease caused by an excessive accumulation for a collagen. The support consists of a bracket and flange supported by a wall support with at least the flange portion thereof extending into the wall cavity. The lenses have adjusting faces which are formed thereon, so that angles formed by the lenses with respect to the optical axes are different from each other, and which are used for an axis-aligning adjustment for the lenses.