A fluorescent water base ink for ink-jet recording to be used for an ink-jet printer contains water, a pigment, a compound having primary or secondary amide group, and a fluorescent dye represented by the following formula :wherein R1 represents OH or NR4, R2 represents hydrogen atom or halogen atom, and each of R3 and R4 represents hydrogen atom or alkyl group. A process control device monitors at least one parameter of the first RF generator and outputs a signal. Such optical-path conversion is performed without using a large-scale optical system. In some embodiments, the reactant fluids are pre-heated by absorbing heat from various components of the vehicle. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.