The present invention relates to a test specimen for testing the through-thickness properties of a fiber-reinforced composite material. Moreover, the systems and methods described herein are capable of operating using short sample collection periods, permitting rapid data collection and finely time-resolved nitrate monitoring over a span of time. The operation may be fully automated. By this means, a sufficient basic supply of the antisurge tower is ensured irrespective of the volume flow produced during filling. Methods of providing hormone replacement therapy and for treating carcinomas, dysfunctional bleeding, uterine leiomyomata, endometriosis, and polycystic ovary syndrome is provided which includes delivering a compound of formula I and a selective estrogen receptor modulator are also described.