A device with a human-machine interface for use as a user control interface, particularly in a an automotive environment, which temporarily indication of the function of a control organ perceptible, when the user begins to actuate it, but has not yet definitively actuated it. A photosensitive material solution of a conductive film is selectively discharged by a droplet-discharging method, selectively exposed to laser light, and developed or etched, thereby allowing only the region exposed to laser light to be left and realizing a source wiring and a drain wiring having a more microscopic pattern than the pattern itself formed by discharging. The web based system, upon receiving appropriate operator commands, automatically processes either from the kinome profiling services database andor GPCR profiling services database, or through a user’s data provided in a supplied template, and provides a visual map of the results against a kinome or GPCRome, which show the familial relationships among kinases and GPCRs. The door controller operates the actuator to open the inlet door to the intermediate door position based on the one or more engine start factors. The operation device may be applied to an electronic book device for flipping of pages.