A patient’s upper airway condition such as snoring and sleep apnea is treated by selecting a particulate material selected for limited migration within tissue and for encouraging a fibrotic response of tissue to the material. The assembly includes a holder frame insertable into the chemical mechanical planarization apparatus, the holder frame having an inner wall. The compounds are useful as modulators of the mu opioid receptor through their binding affinity with that receptor. Other embodiments include three simple planetary-gearsets and five shift-elements of which one or two are brakes. Further, the elongate member passes through a sleeve of the return net, the sleeve being formed at the top of the return net. The normally-open switch turns on or off according to the switch element to control a connection between the charger device and the alternating current power source.