Provided is a sanitary panty including a panty body formed with a front part, a back part and a crotch part located between the front part and the back part; and a support member. The system andor method comprises a probe and a device to stimulate the probe. The invention also includes compositions and methods for mitigating SMN deficiency by targeting inhibition of factors that mediate SMN\u03947-degron dependent degradation of SMN\u03947. A label stripper is positioned adjacent the label feed mechanism at the label applying position and adjacent the path of travel to strip labels from the web when an individual mail piece has entered a label applying position. The outer sleeve includes at least one flexible portion along its length allowing the sleeve to flex to a desired contour.