The present invention includes bit synchronizers and methods of synchronizing and calculating error. This electrode temperature control device does not require components such as a coolant tank for storing the coolant, a pump for supplying the coolant to the processing apparatus, a heater for adjusting the temperature of the coolant and a heat exchanger for exchanging heat between a primary coolant and a secondary coolant. A conductive region is then formed in the insulating layer by implanting silicon atoms into the insulating layer. The holder comes in contact with the clitoris area. The active ingredient in the first spray-dried powder is loaded sufficiently high to compensate for the second spray-dried powder being substantially free of any active ingredient.