The present invention provides a strikingly convenient novel purification method of protein, as compared to conventional methods, which affords automation and high throughput, and a material therefor. More particularly, the method encompasses applying a sample comprising a free and bound analyte fraction to an affinity column capable of selectively extracting the free fraction in the millisecond time domain. A first set of conductors of a first material and design carry low-frequency signals between the base and terminal connector packages. The output signal of the hearing device is then attenuated in dependence on the slope andor height of the respective edge determined. To minimize energy consumption, infrared radiation is led to the polymer or elastomer material, the wavelength of the radiation being so chosen that the radiation penetrates optimally the polymer or elastomer material, but absorbs in the additive, producing the desired reaction in the additive. A comparison is made between the known and the determined spatial locations for at least a subset of the control points.