Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The cartridge contains a resin and pre-colored hardener, which maybe heated to accelerate the cure speed in cold environments if necessary, mixed, and applied to an empty grout joint-line by means of a static mixer tube that acts as a mixer-nozzle. The predetermined criterion may define a length, a depth, and an area. Rotary swaging is performed onto at least a second end of the cylindrical member so as to compress radially to form a male type contact portion thereat. The sensing element is separate from the heater element. The present invention could be characterized as solid-phase distillation.