A guide plate for inserting, into a body, instruments, such as needles, used for medical purposes, comprising a plurality of openings for receiving an instrument; for each of the openings, a sensor arrangement for detecting presence of an instrument when an instrument is received in an opening; and reporting apparatus for reporting sensing of an instrument by each respective sensor arrangement. The invention also concerns cosmetic and dermatological uses of said composition, in particular for preventing or treating actinic skin ageing symptoms. The broadcast information and the auxiliary information are then played back in an interlocked manner with a predetermined timing. 5-9 near the center of each nozzle group in the direction of sub-scanning. The invention also relates to a method for manufacturing and purifying 2,3,3,3-tetrafluoropropene using a hydrofluorination reaction of the saturated or unsaturated compound having three carbon atoms and including at least one chlorine atom in the presence of a fluorination catalyst. The resist composition has a satisfactory effect of suppressing acid diffusion and a high resolution, and forms a pattern of good profile and minimal edge roughness after exposure.