An information handling system has a power supply using a DC-to-DC buck converter. A seal is provided to sealably bond the elements together in a spaced-apart relationship to define a chamber, and an electrochromic material is disposed in the chamber. To map all signal light leaving the substrate onto a single target location, a focusing lens and a second DOE are disposed in the optical path behind the substrate. The variable delay line can also have a ladder configuration of multiple LC subcircuits each having a variable impedance responsive to a control voltage. M and N are positive integers and M is less than N. In preferred embodiments the method provides quantitative analysis of the assembly of regulatory machinery within the context of nuclear architecture and to provide a mechanistic link with biological control.