A semiconductor device is constructed by at least one reference voltage generating circuit for generating a reference voltage, a plurality of input voltage pads for receiving input voltages, a control signal pad for receiving a control signal, and a plurality of input buffers. The present invention provides methods for reduction of CD37-positive cells such as B-cells in an individualpatient using a combination of CD37 antibodyantibodies and ICE. As such the more timely service or substitution for that replaceable element in the system can be provided, thereby allowing costs and service down-time to be minimized. The air cleaning operation of the air cleaning apparatus is restarted when the image forming apparatus is resumed from the night mode. The API is communicated to the virtual machine via the bidirectional link and the API is loaded onto the virtual machine.