A system and method for generating a multidimensional navigation solution utilizes Global Positioning System data to obtain highly reliable and accurate navigational solutions in high interference and dynamic environments, at a performance level which has been heretofore unattainable. The memory cells are erased by Fowler-Nordheim tunneling of electrons into the memory layers. The drain is coupled to an output and precharged to a low voltage. Also provided are methods to decrease the dose of a chemotherapeutic agent by administering the chemotherapeutic agent with a pyrazoloanthrone or a functional derivative or analog thereof that lowers the effective dose of the chemotherapeutic agent. The spelling tool consults a bilingual dictionary to determine possible non-native word translation candidates, a non-native language model to generate probabilities associated with the candidates given the current sentence or phrase context, and a translation model to generate probabilities of how likely a certain native word was intended given the non-native word candidates.