The invention relates to the use of Epidermal Growth Factor in a preferably-injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. A transition between two adjacent side surfaces forms a rounded nose radius surface at a cutting insert corner. In other configurations, each dynode can be coupled to a respective electrometer. By using a parallel routing for a command address bus and an on-die termination bus, the address, clock, and control buses can be adapted in terms of load, so that different signal propagation times on the different buses are avoided to the greatest possible extent. The covered electronic device further includes a printed circuit board having electronic components mounted on it, including the control key.