A method of promoting the healing of a lesion in a smooth muscle, comprises selecting a smooth muscle portion having a lesion, and applying a non-excitory electric field to the portion, which reduces the mechanical activity of the portion. An integrated circuit is designed and implemented such that it is usable at a voltage less than an industry standard Vdd voltage. Mim-1 may be a key signaling protein secreted by osteoclasts that regulates recruitment andor differentiation of osteoblast and osteoclast precursor cells. Accordingly, the PLC network and the wireless network are easily interconnected.