A preventive, therapeutic or improving agent for diseases against which activation of the thrombopoietin receptor is effective or a platelet increasing agent, which contains a thrombopoietin receptor activator represented by the formula : wherein A is a C. The method of remanufacturing of standard length rods includes cleaning the rod with at least one cryogen to eliminate environmental contamination and to assist in workplace safety. 5 mm than in a coarse particle portion having a particle size in excess of 0. Thus, rather than actually spawning threads on the client computer, the mechanism causes jobs to be spawned and executed on the grid.