The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. The base has a contact receiving portion and a first protruding section at one end thereof. Thus, the bi-directional wavelength interleaving optical isolator can provide bi-directional communications by passing a first set of signals in a first direction and a second set of signals in a second direction. The generic Internet based supply chain data viewing engine may be employed in a virtual private supply chain. In an embodiment, the force feedback system includes an actuator to provide a force to the manipulandum in at least one degree of freedom in response to signals received from a computer system. The driving action of the mandrel causes the cushioning material to be dispersed between the mandrel and the liner body, thereby forming the cushioning layer of preselected thickness.