A filler device sub-assembly having a manipulator for manipulating a cap of a container comprising a first and second cap gripper arm and a member for controllably manipulating the cap gripper arms. A modular integrated material blending and storage system includes a first module comprising a storage unit, a second module comprising a liquid additive storage unit and a pump for maintaining pressure at an outlet of the liquid additive storage unit. The biaryl compounds produced using this process possess a high optical purity and are useful as intermediates for medicaments, agrochemicals, etc. Devices related to such methods are also disclosed. A multiplexer converts the encoded data generated by encoder and the 3D information created by the 3D information generator into a predetermined format and outputs the result to the outside.