A personal navigation system including one or more sensors that sense motion of a human and output signals corresponding to the motion of the human and a human-motion-classification processing block that receives sensor data from the one or more sensors. Aspects of the invention include, for example, the identification of IP-10, MIG and certain IL-8 analogues as angiostatic agents, and their use in inhibiting angiogenesis in various systems. The cylindrical crimping member 19b is inserted through openings formed in a first insulating member, a sealing plate, a second insulating member, and a negative electrode collector 18a. Further, the cushion piece is easy to replace.