An interlocking assembly of a voice coil motor for a hard disk drive having an arcuate shaped hollow structure formed by metal injection molding. At least one unreacted reagent or low molecular weight component is removed from this mixture, without removing all of the free protein, to provide a purified mixture that contains the protein-polysaccharide conjugate and free protein. The computing system further performs a TLS handshake over the established TCPIP connection. Interventional devices can be delivered over the guidewire and any embolic debris created and released into the blood stream will enter the filtering assembly. The method can be repeated any number of times, forming second, third and fourth layers of copper.