A method and composition for the treatment of prostate cancer comprises an effective amount of a nonsteroidal antiandrogen and an effective amount of a selective estrogen receptor modulator. The padded license plate screw is designed specifically to replace license plate bolts and used to prevent or minimize bumper damage that would otherwise be caused by license plate bolts in low-impact collisions. In one embodiment, the measured or estimated channel interaction is collected or compiled and saved as a channel interaction matrix.