It is an object of the present invention to provide an immunodeficient animal capable of generating human-derived lymphoid cells, a human-derived lymphoid cell, and a method for producing a human antigen-specific antibody. DC offset correction algorithms are incorporated into the DCR, each algorithm being optimized for a particular receive signal operating environment. By filling the channels with deposited material, the original cross-section and strength of the extrusion can be restored. At least one preferred language applicable to search results generated responsive to the executed search is dynamically determined. The invention also includes an elastomeric polyisoprene product made by the process, such as a surgeon’s glove.