The 15\u03b1,16\u03b1-methylene-17-hydroxy-19-nor-17-pregna-4-en-3-one-21-carboxylic acid \u03b3-lactone derivatives of the present invention possess progestational efficacy. The method comprises the control means determining a current transmission condition, the current transmission condition being one of a current network condition and a current bandwidth requirement of one of the at least one real-time application. In this way, the capability of injecting electrons from the cathode can be improved. The host system receives the associations from the remote systems, stores them, and consults the associations to identify recipients that need to be notified in connection with a lot number that needs to be tracked. Next, all of this information is transmitted to a host site computer that is in communication with the service provider computer and the client computer. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.