The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and enhanced activity of phosphoglycerate dehydrogenase andor phosphoserine aminotransferase. The air-flow channel is disposed between the outer portion and the inner portion of the housing. In addition, when an operator uses a GUI 33 that is displayed in parallel to the entire image of the coronary artery region A to designate an arbitrary scale position on the GUI 33, a CPU 101 calculates positions on the blood vessels A1, A2, and A3 corresponding to the designated scale position. The patterns vary in duration, number, andor shape to correlate to the intensity profile so that a single layer of selectively cured solidifiable liquid material is cured with a substantially equivalent amount of actinic radiation per unit of surface area to provide generally controlled and consistent part quality. The segmented field effect device gives high current drive for a given layout area. For example, in an integrated satellite-based navigation systemwireless network, the location of a mobile unit can be determined by applying WRR processing to at least three distance measurements, where one or more of the distance measurements are satellite-based distance measurements and one or more are wireless network-based distance measurements.