The invention provides novel lavendamycin analogs having the following general formula: and quinoline-5,8-diones having the following formula: Methods of making and using and compositions containing these compounds are also disclosed. The bias may decay in time andor with the number of ratings given to content coming from the new service. The chamber has a reaction product separator impermeable to the solid reactant and a biasing means for biasing reactant products against the separator. The reflective metal layer includes a first composition and a second composition. A wireless connection is established with the uplink device based on the uplink wireless configuration information and, after successful connection establishment, a wireless connection is established with the downlink device based on the uplink wireless configuration information.