A physical quantity sensor detecting physical quantity, such as acceleration or angular velocity, is provided and mounted on, for example, a vehicle. The system includes a machine-readable media comprising instructions which, when executed by the processor, result in determining a plurality of different regularization matrices for a plurality of different regions of an image of the target. Also provided is the use of analogs in therapy, for example hypertension. Moreover, the biotelemetric monitor may operate to analyze and interpret the monitored data to thereby present information with respect to the probable implications of the monitored condition andor make recommendations which may be useful to the patient at that time.