Method of identifying compounds that modulate intermolecular interactions between a target protein and a modifier are disclosed. Notch attachments connect a holding strap at each horizontal end of the spectacle frame so that the spectacle kit can be worn around the wearer’s head external from the protective mask. A dealer is dealt three cards and can take the best two or three card hand out of the three cards. Coupling may be used for slow and fast programming modes. A lubricant feed system allows water to be pumped through passages formed in the pilot tube and steering head. According to the invention, the speed variation device comprises at least two alternate paths for motion transmission to motive axle controlled each by a disengageable coupling.