The present invention concerns novel benzhydryl ether derivatives which exhibit H4-receptor binding activity. One aspect of the present subject matter includes an in-the-ear hearing assistance device adapted to process sounds, including sounds from a wearer’s mouth. This adapter DMA controller allows the system to run in immediate mode which allows the system CPU to talk to the adapter card as if the adapter DMA controller was not there. By generalization and extension of the phase-shift-based precoding, a transceiver is more simplified, and a communication efficiency increases. A valve engaged in the wrench is rotated by the rotary transmission unit and threaded into the screw hole of a sleeve of the gas container, including a guide rod arranged parallel to the column, and a movable frame with its middle portion attached to the guide rod to be free to move in the axial direction, and free to rotate in the circumferential direction via a bearing boss. The elastomeric blends may be mixed by a Y-mix method to improve ozone resistance.