A high voltage and high power boost converter is disclosed. In preferred embodiments, the immunoconjugates comprise one or more anti-CD74 antibodies or antigen-binding fragments thereof, conjugated to a liposome or micelle. The apparatus decides an allotted amount of light for each of the plurality of lasers in accordance with the detected displacement and controls to drive each of the plurality of lasers in accordance with the decided allotted amount of light for each laser. As a result, the fishing lure emits light in all three dimensions due to light refraction and light reflection. The first interconnection scheme is constructed from first metal layers and plugs, wherein the neighboring first metal layers are electrically connected through the plugs. If such a time difference meets or exceeds a first threshold, the an alert is generated.