The present invention relates to the use of pharmaceutical preparations comprising paclitaxel for administration to a human patient in need thereof. The coating is applied to the implant by physical vapor deposition. The touch sensor also includes sense electrodes. The shaft member 150 is guided by a guide member 170 and drives a valve member 160 disposed within a valve chamber 161. A microcomputer 13 selects an attenuation coefficient \u03b11 or \u03b12 in accordance with the sampling frequency detected by the DIR 10, and attenuates the levels of surround headphone output signals Lo and Ro on the basis of the selected attenuation coefficient \u03b11 or \u03b12. As such, the processing module segments the input text stream into single topic groupings of words, where each grouping is of a respective single topic.