A digital power gating system for performing power gating to reduce a voltage of a gated supply bus to a state retention voltage level that reduces leakage current while retaining a digital state of a functional circuit. A profiling database may be constructed for helping to identify the vital data-containing windows of both popular and obscure application programs. The circuit connected to the cross-coupled regenerative latch operates as a voltage follower during an acquisition mode and as a cascode amplifier stage during the latching mode.