The present application discloses a substrate that includes a molecular layer of regularly spaced size-controlled macromolecules comprising a polymer comprising branched and linear regions in which a plurality of termini on the branched region are bound to the substrate, and a terminus of the linear region is functionalized. The signaling processor receives a signaling message and searches the cache memory with a called number to determine whether or not the called number has an associated location route number or if a query is required. The subscriber locations may be predefined by the called party. The cells are oriented in the pixel such that light from the pixel is perceivable in six directions, thereby creating a three-dimensional light source. A dual-dispensers system having two reagent cartridges and two dispensing lines is included for simultaneous or selective dispensing of reagents for multiple diagnostic testing. A second retaining arrangement is operable to lock the other end of the crimping drum to the housing.