A dynamic self-configuring system for collecting metering data comprises a collector meter. In some aspects, semiconductor devices are thermally coupled directly to thermally conductive substrates without intervening dielectric or insulative structures. The present invention also relates to formulations of methylglyoxal and imino acid conjugates of methylglyoxal that can be used for the treatment and suppression of malignant diseases including but not limited to the cancers of Colon, Prostate, Pancreas, Lung, Oral cavity, Glioblastoma, and Leukemia. An outer portion of the cylindrical housing is transparent. In response to receiving the user input, the third display area is updated with output data generated by applying the modified data transformation to the input data.