A developer conveying device includes a rotatable developer conveying body including a shaft portion and a blade portion provided on the shaft portion for conveying a developer. The ADC system includes a first, a second, and a third ADC circuit, and a digital interface circuit. The liquid is positioned within the electrical fields. A ramped transition from an anvil to an anvil slot avoids misfiring when the end effector has clamped too much tissue, yet assists in successfully clamping a slightly excess amount of tissue. A compound represented by the following formula I or a pharmaceutically acceptable salt thereof, or a solvate thereof:wherein each symbol is as described in the specification.