Methods of manufacturing microelectronic device including, in one embodiment, forming a gate electrode over a substrate having an insulating layer interposing a bulk semiconductor portion and a thin semiconductor layer, and removing at least a portion of the thin semiconductor and insulating layers, thereby defining a pedestal comprising a portion of the thin semiconductor and insulating layers. The IC includes an MBIST controller and a plurality of memory arrays. The catheter introduces the energy delivery element into the patent foramen ovale of a patient’s heart.