A curved conveyor is provided which includes at least a pair of supports arranged so that their axis lines mutually intersect at a desired angle, and an endless curve belt having a flat fan shape matching the angle which is supported on the respective supports so as to be able to run. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease. The settable mixture flows from the mixing head to fill the mold tool.