The invention describes therapeutic compositions including a lactic acid-producing bacteria, such as isolated Bacillus coagulans, in combination with a cholesterol-reducing agent for use in reducing LDL cholesterol and serum triglycerides. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. When receiving the connection request, the image forming apparatus determines whether or not the user has been authenticated based on the received authentication information. The signal defect model is generated from a number of sample playback signals. The two storage receptacles are adapted to permit removal of the aerobic adhesive and the hydrophilic material from the receptacles for mixing together the fixing agent.