Fragrance control is provided by articles of manufacture including various fragrancing objects, methods of using such objects, and systems that employ one or more such objects. The controller is configured to control the switch and a transition between or among the plurality of light modes in response to the signal received by the receiver. The non-replicating vector may be formulated with a pharmaceutically-acceptable carrier for in vivo administration to the host. These water soluble derivatives are herein denominated as \u201cCombretastatin A-4 Prodrugs\u201d. The first and second spacers cooperate to provide a spatial relationship among the MCP, phosphor screen and photocathode for effective operation of the image intensifier tube.