A medical device for preparing a bone of a joint of a patient includes a numerically controlled instrument having a housing including a controller, a processor and a tool driver, a patient-specific reference guide removably couplable to the housing, and a cutting tool removably coupled to the tool driver. Also provided is a process for manufacturing the same wherein water in the reaction bath is replaced by a non-water washing agent having little or no hydrogen bonding capability to inhibit the formation of hard agglomerates in the ceramic powder. The tablet accommodation parts are rotatably connected to each other. The digital watermark is embedded in the digital imagery through modifications to at least some data representing the digital imagery. The combined flavorcolor component and optional sweetener component is then added. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 15120100 with another soybean cultivar.