Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal’s angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. Neutral form text also removes hidden markup such as line breaks, paragraph breaks or page breaks. Corresponding system are also described. The camber, in turn, is parallel to a curve that is defined by two camber lines. If transmitting while PWM is on, the modem needs a large coupling impedance andor a large signal injection.