An optical fiber for use with a laser device including a source of light energy, as well as a method of making such optical fiber, where the optical fiber has a proximal end in communication with the light source and a diffuser portion positionable at a treatment site. A method is provided to convey and maintain information used to synchronize the packetization and burst operations within the network. Also provided herein is a method of contacting a sensor to a patient’s skin and method of manufacturing a sensor. If a match is found, the application server may provide an existing connection to the application, whereas if no match is found the application server may provide a new connection. The machine includes at least one line associated with the device for fluid removal for returning the removed fluid to an upstream position in the flow path and at least one further line associated with the device for fluid supply for supplying the fluid from a further downstream position in the flow path.