The present invention relates to an antibody or functional fragment thereof which binds to a mammalian CC-chemokine receptor 2 or a portion of the receptor and blocks binding of a ligand to the receptor. The MEMS devices comprise a substrate and a MEMS filter device mechanically suspended above a major surface of the substrate. Accordingly, reminders can be configured by custodian devices and delivered to subservient devices if certain predetermined conditions or criteria are satisfied in connection with the presence information. The node of the graph is matched based on the time-based information being at least partially within the first time interval. The acquired magnetic resonance data are reconstructed to produce reconstructed images corresponding to the plurality of slices. The controller includes a first controller that predicts the optimal turn-on and turn-off time of the first synchronous rectifier as a function of voltage measurements of the previous switching cycle and the timing of the pulse width modulator signal in the current switching cycle.