A computerized positioning and cutting apparatus and method for automatically cutting structures to predetermined lengths with a minimum amount of scrap for a given project. A vehicle navigation device 50 is connected in communication with a provider 60 for offering transmission service of map information which includes the current POI information pertaining to locations on a map where the points of interest are located. The invention also provides methods for the control or prevention of hypertension, angina pectoris, ischemia, arrhythmias, and cardiac insufficiency in a patient by administering a compound, or composition, of the invention to an individual in need of such treatment.