In one embodiment, a method is provided that may include one or more operations. for ATs of different QoS levels, the transmission rate of the ATs are adjusted, thereby the ATs of different QoS levels are allowed to enjoy different reverse highest rates and reverse average rates, and the QoS of the AT interactive reserve data is improved. A signal driver is connected to the signal wire. The frame includes one or more apertures configured to receive an LGA interposer for electrically connecting the two substrates. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.