The present invention relates to an aqueous dispersion of a water-insoluble coloring material having superior shelf life stability which is suitable to an ink for ink-jetting, an ink composition superior in shelf life stability and discharge property, a method for inkjet recording using said ink composition, and recorded article obtained thereby. The invention provides pharmaceutical compositions containing the compounds and the methods for employing them as medicaments, particularly in the treatment of human and animal cancers. The method of the present invention amplifies miRNA directly from stool specimens without any prior miRNA extraction. Providing elastically deformable segments of high elasticity dispersed along the leading edge combined with regions of lower elasticity maximizes responsiveness and control by allowing leading edge deformation in response to user applied force, while the providing sufficient support to maintain kite stability.