The invention relates to the use of a polyolefin composition comprising a propylene-ethylene random copolymer having an ethylene content of 0. In addition, the light-emitting diode arrangement has at least one heat-conducting element which is suitable to carry away the heat generated by the light-emitting diode chip, and at least one cooling apparatus which is suitable to carry heat away from the heat-conducting element. This architecture is built upon an object-oriented call model which is defined as a small set of extensions to the standard Java Telephony API call model. Also provided are methods of identifying selective mGlu5 antagonists that are useful for treating neuromuscular dysfunction of the lower urinary tract in a mammal.