Disclosed are compounds which bind \u03b14 integrins, preferably VLA-4. Embodiments of a system including a computer, which includes a first USB stack, a first remote host controller function implementing a first virtual USB port, an abstraction of a remote host controller, and a host controller, coupled with said computer, operating in combination with said abstraction of a remote host controller as a USB host controller of said computer, is described. The method also comprises reconditioning each of the digital discs transferred to the workstation with at least one worktool operable to remove a portion of the protective coating of each of the digital discs without removal of the data underlying the protective coating.