An improved voltage boosting circuit operates entirely from a single, common VCC voltage supply. The circuit module is coupled to the battery cell by lead plates. The anti-KC-4 monoclonal antibody is used in diagnostic kits for cancer and in in vivo methods of imaging and treating a primary or metastasized cancer, and in vitro diagnosis and ex vivo purging neoplastic cells from a biological fluid. In addition, since the electronic device is detachable from the spindle through the coupler, the electronic device can be coupled to the coupler after the electronic device is reversed by the rotation about one rotation axis. Also disclosed is a method of joining a fastening system to an item.