An optical waveguide fiber having a high threshold for stimulated Brillouin scattering. Such MEMS in-plane resonators may be fabricated using conventional surface micromachining techniques and high-volume wafer fabrication processes and may be configured for liquid applications, gas sensing, or other applications. The interconnection controller in each cluster comprises a plurality of protocol engines for processing transactions. The results of genotyping the target nucleic acid using the optimal probe pairs for each mutation site are statistically robust to errors. At first a compound comprising hydroxyalkyl amide units and carboxylic acid units is obtained by reacting a cyclic anhydride and an alkanolamine in a mixing device and that secondly the binder composition is obtained by mixing the compound and a polymer in a second mixing device.